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== 3. Cellular Signaling: The Language of Immunity == The innate and adaptive systems do not operate in isolation; they are deeply integrated through complex cellular signaling. * '''Cytokines:''' A broad category of small proteins secreted by immune cells that affect the behavior of other cells around them. They regulate the intensity and duration of the immune response. * '''Chemokines:''' A specific type of cytokine that acts as a chemical beacon, guiding circulating white blood cells directly to the site of infection or tissue damage. * '''Antigen Presentation:''' The critical bridge between the two systems. After a macrophage or dendritic cell digests a pathogen, it displays fragments of the pathogen's proteins (antigens) on its surface using a structure called the Major Histocompatibility Complex (MHC). It physically travels to the lymph nodes to "present" these antigens to T cells, officially initiating the adaptive response.
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